Fibric acid, also known as fibrates or fibric acid derivatives, are a typical class of drugs that helps in lowering cholesterol and has potential effects on the overall lipid panel. Fibric acid follows a complicated process for lowering the cholesterol levels. It activated peroxisome proliferator-activated receptor alpha, a type of protein that helps in controlling the cholesterol numbers.
The presence of this protein actually helps in activating lipoprotein lipase, a typical enzyme that decreases the amount of apolipoproetin C-III in the body. This in turn helps in decreasing the formation of triglycerides and VLDL cholesterol, thereby encouraging the breakdown of all the lipids. It further promotes the presence of HDL or good cholesterol levels as well.
There are different brands of fibric acid available today in the US market. Fibric acid is also known for its ability to lower triglycerides and have positive effects on the lipid profile. Fibric acid derivatives can be used singly, or in combination with different types of lipid lowering agents for lowering the cholesterol levels effectively.
Fibric acid derivates should not be taken by patients with gallstones, gallbladder diseases, kidney problems or liver diseases. It is only for people with higher levels of cholesterol and triglycerides. |